N-Acetylcysteine

Preventing complications of coronary angiography with N-acetylcysteine

Tagged:  

Focuses on prevention of complications of coronary angiography with N-acetylcysteine. Effect of the administration of contrast agents during coronary procedures; Mediation of free radicals in ne...

N-acetylcysteine and Myocardial Infarct

Tagged:  

Reference: Sochman J, Vrbska J, Musilova B, Rocek M. Infarct size limitation: acute N-acetylcysteine defense (ISLAND Trial): preliminary analysis and report after the first 30 patients. Clin Cardiol 1996; 19:94-100.

Protective effect of N-acetylcysteine (NAC)

Tagged:  

The use of N-acetylcysteine (NAC) 7 days after drinking alcohol: 1) reduced lipid peroxidation, 2) elevated the reduced glutathione level in the liver and in red blood cells, 3) and increased the activity of reduced glutathione-related enzymes in the blood, red blood cells and in the liver. Without NAC, drinking alcohol increased the concentration of the lipid peroxidation products, decreased the liver glutathione activities, and reduced the glutathione concentration and total antioxidant status. Alcohol is oxidized to formaldehyde and then to formate.

N-acetylcysteine (NAC) inhibits LDL oxidation

Tagged:  

We investigated the ability of NAC to inhibit LDL oxidation. NAC inhibited in vitro LDL oxidation induced by copper sulfate, 2,2'-azobis(2-amidinopropane) dihydrochloride, and UV light, and protected LDL against depletion of antioxidant vitamins. Glutathione was similarly effective against copper-mediated LDL oxidation. Sequential additions of NAC slowed down LDL oxidation more effectively than the initial addition of the same total dose. NAC reduced antibody formation during the oxidation of native LDL by oxidized LDL.

Syndicate content