Receptors

These proteins are responsible for signal detection and translation into other type of signal. Sometimes these proteins are active only in complex with low molecular weight compounds. Very well known member of this protein family id rhodopsin - light detecting protein. Many receptors are transmembrane proteins.

Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention

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The human vitamin D receptor (VDR) is a key nuclear receptor that binds nutritionally derived ligands and exerts bioeffects that contribute to bone mineral homeostasis, detoxification of exogenou...

Muscarinic Receptor Activity of Some Malaysian Plant Species

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Muscarinic receptor binding activity was tested on 224 plant extracts obtained from more than 50 plant families found in Malaysia. The plant extracts were evaluated by a 96-well microplate filtra...

Mitochondrial oestrogen receptors and their potential implications in oestrogen carcinogenesis in human breast cancer

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Background. Prolonged exposure to oestrogens (17?-estradiol)(E2), xenoestrogens, hormone replacement therapy and contraceptives has been recognized as a key aetiological factor of human breast ca...

Lycium Barbarum Inhibits Growth of Estrogen Receptor Positive Human Breast Cancer Cells by Favorably Altering Estradiol

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Selective estrogen receptor modulators represent accepted therapy for estrogen receptor positive (ER+) breast cancer, exhibit adverse side effects, and reduce patient compliance. The use of phyto...

Canarosine: A new guanidine alkaloid from Canavalia rosea with inhibitory activity on dopamine D1 receptors

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A new acyclic guanidine alkaloid, canarosine (1), together with five known compounds, ?-sitosterol (2), stigmasterol (3), daucosterol (4), epi-inositol 6-O-methyl ether (5), and rutin (6), were i...

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