Mercury Fillings and Manic Depression


Mercury Fillings and Manic Depression

Reference: Siblerud RL, Motl J, Kienholz E. Psychometric evidence that dental amalgam mercury may be an etiological factor in manic depression. J Orthomolec Med 1998; 13:31-40.

Summary: A group of 20 male and female patients diagnosed with bipolar disorder participated in this study. Eleven chose to have their mercury amalgam fillings removed completely, and the rest opted to either have sealants placed over the fallings or to have a placebo sealant installed. The nine subjects who took the sealant option were randomly assigned to receive placebo or actual sealant. Everyone was given a multinutrient supplement, though the amalgam removal group's supplement additionally contained garlic and glutathione peroxidase -- both have shown promise as mercury chelators. Before the study and six to eight months later, the participants took a series of psychological tests designed to judge changes in persons with bipolar disorder. On the majority of scales on the Minnesota Multiphasic Personality Inventory-2 there was a significantly superior improvement in the amalgam removal group than in the sealant group. The same was true regarding the Millon Clinical Multiaxial Inventory-II. The Symptom Check List 90 showed a significant improvement in all nine dimensions in the amalgam removal group compared to the sealant group. There was a 390% increase in oral cavity mercury vapor levels in the amalgam removal group after chewing gum (and before the amalgams were actually removed) compared to a 106% increase in the sealant group. The authors conclude mercury amalgams may significantly contribute to the etiology of bipolar depression.

Natural Product Research Consultants, Inc.


By E. Yarnell

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