ANTI-AGING MEDICINE UPDATE: AGING IS NOT INEVITABLE

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Anti-Aging Medicine Update: Aging Is Not Inevitable!

A4M News

Due to the extensive demand to participate in the American Board of Anti-Aging Medicine certification exam and for information on clinical practice of anti-aging medicine generated at our December 1997 conference, A4M will host its first Bi-Annual Conference on Anti-Aging Medicine August 14-16 at the Meadowlands in New Jersey. The second sitting of the Board examination will be held, and the conference theme will be on office-based anti-aging medicine. A4M is currently developing Lexcore, a computer software program that will link all clinical anti-aging medical practitioners, to cross reference research and treatments.

IGF-I and Prostate Cancer Controversy

In the first issue of the International Journal of Anti-Aging Medicine L. Cass Terry, MD, PhD, PharmD, Professor of Neurology and Physiology at the Medical College of Wisconsin published results of a study in which he found no association between IGF-I (Insulin-like growth factor) levels and PSA (prostate specific antigen), which is today's most accurate screening test for prostate cancer. Dr. Terry conducted this study in response to a recent article in Science which suggested a connection between elevated IGF-I levels and prostate cancer, and has caused concern for those taking human growth hormone, which stimulates the production of IGF-I in the liver. However, Dr. Terry concludes: "Giving growth hormone as an anti-aging remedy...does not appear to increase the risk of cancer."

Even Moderate Exercise Contributes to Longevity

In the first study to separate the influences of heredity and exercise on longevity, Dr Urho M. Kujala of the University of Helsinki in Finland tracked 16,000 healthy sets of twins for an average of 19 years. Those twins who exercised regularly -- at least 2 half-hour brisk walks per week -- cut their risk of death by 44%. Even occasional exercisers were 30% less likely to die than their control group (sedentary) twin, despite any genetic predispositions to early death. Dr Kujala has published his findings in The Journal of the American Medical Association (Vol 279, No 6).

Anti-Aging Research at the NIA

The National Institute on Aging is sponsoring two major anti-aging studies and is soliciting applications for investigations into the anti-aging properties of DHEA as well (program announcement number PA-97-051). According to Frank Bellino, PhD, a study on the effects of human growth hormone on adults aged 60-70 is in its last stages of trials, and the data is supportive of the theory that hGH replacement helps restore youth to the body. Dr Bellino feels that more research is needed, to assess side effects and to develop protocols for adjusting dosage.

George Ross, PhD reports that the 11 year-old NIA-funded study on the anti-aging effects of caloric restriction on monkeys indicates that "reduced feeding can slow the rate of aging in primates." He cites an observational study of caloric restriction in humans as indicating that it "can be beneficial to humans." These studies have taken care to undernourish without malnourishing, so that the diet is 30% restricted relative to body weight, and fortified with the necessary vitamins, minerals, and trace elements.

Chromium Supplementation to Treat Type 2 Diabetes

With adult onset diabetes one of the leading causes of premature death, a recent study published in Diabetes (Vol 46, No 11), the Journal of the American Diabetes Association, showed promising results in controlling diabetes with chromium picolinate, an essential nutrient involved in normal carbohydrate and lipid metabolism. Over a four-month period, a group of 180 adults were given high levels of chromium supplements of 1000 mg daily. Glycated hemoglobin levels and serum cholesterol levels dropped significantly in these patients, as well as insulin and glucose levels.

Townsend Letter for Doctors & Patients.

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By Ronald M. Klatz

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