Functional Medicine Update: Functional Disturbances of the Liver & Lymphatic System

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Functional Medicine Update: Functional Disturbances of the Liver & Lymphatic System

Correspondence: Center for Biological Energetics

P.O. Box 155

Milford, PA 18337

717-296-6316 / Fax 717-296-8257

The concept of functional medicine embodies interrelationships between various organs, systems and cellular networks of the body. It is mainly a discussion of functional rather than pathological aberrations. Most "official" medical ills give signs of functional deficits long before pathology or disease can be medically diagnosed. Long before pathology is observed, there are losses in functional integrity of the organ systems with increasing sensitivity to the environment and a gradual reduction in vitality. Hence, the concept of restoring a synchronous correlation between all bodily systems is preventative in scope and practice. This column discusses functional disturbances of the liver, gallbladder, lymphatic system and the immune system.

When hepatic detoxification mechanisms are not working efficiently, patients typically complain of headaches, arthralgias, inability to concentrate, visual changes, hearing disorders, kidney problems, fatigue, myalgias and muscle pain which is usually located in the trapedius or rhomboid muscles. Contrary to the idea that often prevails, the absence of abnormal liver enzymes (SGOT, SGPT, and GGTP) does not reveal anything about the presence of functional or adequate detoxifying ability of the liver. These enzyme levels relate to pathology and cannot assess hepatic detoxification pathways and rate of toxin elimination and excretion through the hepatic duct system.

Voll-EAV testing on the liver and gall bladder meridians provides accurate information regarding the functional activity of the liver and gall bladder. Each meridian can be challenged with specific toxins, antigens, nosodes or microbes and the response to that stressor can be measured. This type of functional testing will give the physician valuable clues regarding the causative factors in a given illness.

Cytochrome P450 enzyme activity transforms specific toxins into biotransformed intermediates that can ultimately be excreted as nontoxic derivatives through the hepatic duct system and the kidneys. Studies by Bland (1994) show that individuals with the lowest cytochrome P450 enzyme activity are the slowest detoxifiers (the slowest eliminators of toxins). In trying to understand how the liver functions as a detoxifying organ, it is important to consider biliary physiology and meridian dynamics (Figure 1). The rate of clearance from the body of environmental toxins or bacterial endotoxins is directly dependent upon the following:

(1.) The pH of the liver cells and bile as an acid pH will block or inhibit cytochrome P450 enzyme activity.

(2.) The production of and flow of bile through the hepatic ducts into the gall bladder (blocked or impeded by duodenitis or other infections of the duodenum).

(3.) The overall energetic health and functional activity of the liver, intestines and kidneys.

(4.) Proper lymphatic drainage and intestinal elimination of toxins.

By means of chemical activity known as oxidation, reduction, and conjugation, the liver converts toxins to a water-soluble form for excretion by the kidneys or elimination through the gall bladder and hepatic ducts. By means of adding oxygen, excessive amounts of hormones produced in response to the stress of life can be inactivated or made to form salts by the removing of oxygen, which is reduction. In addition, bacteria, toxins and hormones out of balance can be inactivated by conjugation which is the joining of various substances in order to restrict their activity.

The liver helps to maintain health and homeostasis by rapidly metabolizing nutrients, xenobiotics, and wastes that are absorbed via the gut. It also synthesizes and provides the body with most of the plasma proteins. When the liver is debilitated and low in protein and sugar, the nervous system is called upon to release protein and the kidneys are overworked (commonly revealing a stress response with Voll testing). Furthermore, the depletion of protein precipitates neuritis, neuralgias, nervous exhaustion or nervous breakdown while the excess of endogenous toxins can cause false neurotransmitter activity and brain biochemical dysfunctions. Other conditions such as arthritis, hypertension, gastric and duodenal ulcers, arteriosclerosis and skeletal muscle spasms are also caused by this abnormal physiology.

The liver is also responsible for detoxifying the intestines by filtering inflammatory irritants caused by incomplete digestion. As a result, when the liver is overburdened by the fermentation and putrefaction of maldigestion, it is less able to neutralize environmental toxins. These toxins circulate throughout the body, irritating tissues, causing inflammation and are deposited in the lymphatic system (lymph nodes) and connective tissue.

As the liver's toxic load increases through multiple exposures to toxins, the capacity of the liver can be exceeded. As a result toxins become impacted in the lymphatic system and liver, reducing functional activity of the liver and immune system. Hepatoprotective tonics (Rejuvagest) that enhance the toxic substances, and protect the liver from further damage are helpful in these disorders.

When the biliary tract is congested or irritated, byproducts of cytochrome P450 activity (superoxide) are converted by the liver to hydroxyl radicals which damage the liver and other oxygen-sensitive tissues. It is critically important to assess biliary function before a patient is given a detoxification program or is told to fast on water or juices. In addition, promoting lymph drainage with herbal oil packs must accompany any detoxification approach. This approach prevents reactive oxygen species from damaging the liver, endocrine, immune and nervous systems and insures that toxins will be eliminated and excreted from the body.

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Clinical Findings: Drainage of the Lymphatics and Liver

The immune system employs a large population of white blood cells that have exquisite specificity to virtually any antigen it encounters. The healthy immune system tailors the quality of its response to the nature of the pathogen and the way in which it infects the body. For example, viruses, certain kinds of bacteria and parasites, can establish their infections inside the host's cells, where antibodies cannot reach them. To rebuff these organisms, the healthy cell has proteins called major histocompatibility complex (MHC) molecules. MHC molecules signal that the cell is infected and travel to the lymph nodes, where they recruit lymphocytes for the immune response. Thus, the recognition of the MHC molecules on the surface of the cell and its ability to penetrate lymph nodes are critical to the initiation of all immune responses. However, when the liver detoxification networks are inadequate, toxins tend to harden and irritate the lymph nodes, thereby interfering with the ability of MHC molecules to penetrate and initiate an optimal proper immune response.

The thymus gland and lymph nodes -- major centers of immunity -- are connected to nerve fibers that help to stimulate and amplify immune responses to infection. In addition, the parasympathetic nervous system provides the primary innervation to the lymphatics. The reticuloendothelial system (RES), located primarily in the walls of the intestines, liver, spleen, lungs and connective tissue, contains macrophages that play an active role in helping the body clear viruses from the blood. As described previously, improving the liver's ability to excrete and eliminate toxins is important for the optimal functioning of the liver's RES network.

The processing of antigens is intimately tied to the mechanisms that synthesize and recycle all proteins through the liver networks. Greater understanding of antigen processing deficits and protein depletion in the liver could eventually take the form of better treatments for many immune-related disorders. The ability of MHC molecules to participate in antigen processing is a consequence of their structure and synthesis. As might be expected, amino acid deficiencies due to protein maldigestion and functional disorders of the liver and gall bladder can create a cellular shortage of MHC molecules and block antigen pathways. Enhancing the processing of antigens is theoretically possible by improving lymphatic and liver function while providing the body with superior biomolecular nutrition.

The therapeutic value of using herbal oil packs on the abdomen has been demonstrated in over 75 cases of liver, biliary and lymphatic congestion. The most dramatic results are seen in viral disorders of the immune system and liver. The program involves using three herbal-oil formulations to enhance parasympathetic nervous system function (motor innervation to the lymphatics). Patients were tested before and after treatment with BERM testing. The analysis of these cases showed that the Synchronzyme BioEnergetic Kit was clinically effective in the following ways:

(1.) It helped to increase elimination of impacted toxins from the entire gastro-intestinal tract.

(2.) It helped to energize the liver, gall bladder and other organs, thereby improving their assimilation and functional activity.

(3.) It helped to reduce the energetic blockages of scar adhesions caused by previous surgery of the appendix or gall bladder, thereby allowing for an increased flow of bile or lymphatic fluids.

(4.) It provided relief from duodenal or gastric pain.

(5.) It increased lymphatic drainage and reduced inflammation.

(6.) It was effective in drawing out acid-based toxins from the body and provided superior detoxification and drainage that exceeded any previously used homeopathic system of detoxification.

(7.) It provided relief from insomnia, nervousness and anxiety in patients who did not respond to other natural approaches.

(8.) It enhanced the immune response as evidenced by the increase in lymphocyte activity in patients with immunosuppression.

(9.) It improved the electrical conductance and had a harmonizing effect on the entire acupuncture system of the body as evidenced by before and after Voll-EAV testing.

In my clinical evaluation and research with this approach, I have found that most patients have demonstrable improvement in thier physiological function within 14 to 21 days after starting therapy. During this clinical evaluation, specific biomolecular nutrition was used to provide high quality nutrition that is well-tolerated (no potential allergens) and easy to assimilate (synchronzyme process) through the intestinal villi into the cellular matrix. By using biomolecular nutrients that are synchronized, signal transduction is enhanced at the cellular and organ-specific level, physiological function is supported, and the biological response is modified in a positive direction. Furthermore, detoxification of the lymphatic system and the hepatic duct system of the liver result in improved functional capacity, reduced symptoms and improved health outcomes.

After clinically applying every known colon detoxifier and herbal lymphatic cleansing agents with only limited success, I have developed a three-part therapeutic system to enhance immunity and lymphatic drainage. This system consists of ingesting an herbal oil complex, using a penetrating herbal oil complex with an abdominal heating pad (non-electric), while simultaneously stimulating hepatic duct drainage. This program, known as the Synchronzyme BioEnergetic Kit improves coordination of the functioning of major organs, glands and systems of the body. Its energetic properties are enhanced by the Synchronzyme(TM) process which organizes the spectrum of energies in its immediate proximity by organizing the matrix of atoms in the herbal oil complex, Kirlian photography demonstrates that the herbal oils radiate a wide spectrum of energy (frequencies) which may explain why it works so efficiently in balancing meridian pathways.

Stress and environmental toxins can damage liver cells and congest lymph nodes, compromising the integrity and proper drainage of the lymphatic system. Detoxifying the liver and lymphatic system while providing superior biomolecular nutrition to the liver, can provide physicians with an unparalleled method of lymph cleansing and immune enhancement.

Townsend Letter for Doctors & Patients.

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By Paul Yanick

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